Article
WinHAP2: an extremely fast haplotype phasing program for long genotype sequences.
BMC bioinformatics - 30 May 2014
Pan Weihua, Zhao Yanan, Xu Yun, Zhou Fengfeng
Abstract excerpt
BACKGROUND: The haplotype phasing problem tries to screen for phenotype associated genomic variations from millions of candidate data. Most of the current computer programs handle this problem with high requirements of computing power and memory. By replacing the computation-intensive step of constructing the maximum spanning tree with a heuristics of estimated initial haplotype, we released the WinHAP algorithm...
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