Article
Genomic characterisation, chromosomal assignment and in vivo localisation of the canine high mobility group A1 (HMGA1) gene.
BMC genetics - 23 Jul 2008
Beuing Claudia, Soller Jan T, Muth Michaela, Wagner Sigfried, Dolf Gaudenz, Schelling Claude, Richter Andreas, Willenbrock Saskia, Reimann-Berg Nicola, Winkler Susanne, Nolte Ingo, Bullerdiek Jorn, Murua Escobar Hugo
Abstract excerpt
BACKGROUND: The high mobility group A1 proteins (HMGA1a/HMGA1b) are highly conserved between mammalian species and widely described as participating in various cellular processes. By inducing DNA conformation changes the HMGA1 proteins indirectly influence the binding of various transcription factors and therefore effect the transcription regulation. In humans chromosomal aberrations affecting the HMGA1 gene...
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