Article
Evaluation of tumor microsatellite instability in laryngeal cancer using five quasimonomorphic mononucleotide repeats and pentaplex PCR.
Advances in medical sciences - 1 Jan 2008
Rózańska-Kudelska M, Walenczak I, Pepiński W, Sieśkiewicz A, Skawrońska M, Rogowski M
Abstract excerpt
PURPOSE: To determine microsatellite instability (MSI) in squamous cell carcinoma of the larynx. MATERIAL AND METHODS: The study was performed in a group of 30 male patients, aged 42-47 years. All patients underwent total laryngectomy with lymph nodectomy. Histologically all tumors were squamous cell carcinomas. Detection of MSI was based on comparison of allelic profiles generated from amplification of matching...
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