Article
Environmental and genetic susceptibility to MLL-defined infant leukemia.
Journal of the National Cancer Institute. Monographs - 1 Jan 2008
Ross Julie A
Abstract excerpt
The study of rare cancers, including retinoblastoma, angiosarcoma, and vaginal clear cell carcinoma, has contributed greatly to our understanding of cancer mechanisms. Infants with leukemia may represent another important rare group. The majority of infants with leukemia have MLL gene rearrangements in their leukemia cells, and there is unequivocal laboratory evidence that these arise in utero. There is...
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