Article
MnSOD gene polymorphism association with steroid-dependent cancer.
Pathology oncology research : POR - 1 Mar 2009
Bica Claudia Giuliano, de Moura da Silva Leonardo Leiria, Toscani Nadima Vieira, da Cruz Ivana Beatrice Manica, Sá Gustavo, Graudenz Márcia Silveira, Zettler Cláudio Galleano
Abstract excerpt
Oxidative stress enhances carcinogenesis due to DNA damage. Manganese superoxide dismutase (MnSOD) Val16Ala polymorphism has been recently associated with breast and prostate cancer. The role of oxidative stress in male breast cancer is poorly investigated due to the low prevalence of this neoplasia. We studied the relationship between prostate cancer (PC), male (MBC) and female breast cancer (FBC) and this...
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