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Article

Del(6)(q22) and <i>BCL6</i> Rearrangements in Primary CNS Lymphoma Are Indicators of an Aggressive Clinical Course

21 Jul 2008

Abstract excerpt

PURPOSE: Primary CNS lymphoma (PCNSL) is an aggressive lymphoma but clinically validated biologic markers that can predict natural history to tailor treatment according to risk are lacking. Several genetic changes including BCL6 rearrangements and deletion of 6q22, containing the putative tumor suppressor gene PTPRK, are potential risk predictors. Herein we determined the prevalence and survival impact of...

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Identifiers

PMID: 18645192
DOI: 10.1200/jco.2008.16.1455

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