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Article

The type III pantothenate kinase encoded by coaX is essential for growth of Bacillus anthracis.

Journal of bacteriology - 1 Sept 2008

Paige Carleitta, Reid Sean D, Hanna Philip C, Claiborne Al

Abstract excerpt

In Bacillus anthracis, the novel type III pantothenate kinase (PanK(Ba); encoded by coaX) catalyzes the first committed step in coenzyme A biosynthesis. We have demonstrated by analyzing the growth characteristics of a conditional coaX mutant that PanK(Ba) is an essential enzyme, thus contributing to its validation as a new antimicrobial target.

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Identifiers

PMID: 18641144
DOI: 10.1128/JB.00860-08
PMCID: PMC2546792

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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