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Article

Facial clefting in Tp63 deficient mice results from altered Bmp4, Fgf8 and Shh signaling.

Developmental biology - 1 Sept 2008

Thomason Helen A, Dixon Michael J, Dixon Jill

Abstract excerpt

During embryogenesis, the transcription factor Tp63 is expressed in the basal cells of multiple epithelial tissues. In humans, mutations in TP63 have been identified in five distinct human developmental disorders that are characterized by limb abnormalities, ectodermal dysplasia, and facial anoma...

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Share to Bone Morphogenetic Protein 4
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 18634775
DOI: 10.1016/j.ydbio.2008.06.030

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18634775-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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