Article
Association study between genetic variants at the VAMP2 and VAMP3 loci and bipolar affective disorder.
Psychiatric genetics - 1 Aug 2008
Abou Jamra Rami, Gobina Carl Motinda, Becker Tim, Georgi Alexander, Schulze Thomas G, Schmael Christine, Cichon Sven, Propping Peter, Rietschel Marcella, Nöthen Markus M, Schumacher Johannes
Abstract excerpt
OBJECTIVES: Vesicle-associated membrane proteins 2 and 3 (VAMP2 and VAMP3) are required for the release of D-serine, a competitive agonist of the neurotransmitter glycine at the glutamatergic N-methyl-D-aspartate receptors. Several lines of evidence point to an involvement of altered D-serine lev...
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