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Directed and Systematic Differentiation of Cardiovascular Cells From Mouse Induced Pluripotent Stem Cells

15 Jul 2008

Abstract excerpt

BACKGROUND: Induced pluripotent stem (iPS) cells are a novel stem cell population induced from mouse and human adult somatic cells through reprogramming by transduction of defined transcription factors. However, detailed differentiation properties and the directional differentiation system of iPS cells have not been demonstrated. METHODS AND RESULTS: Previously, we established a novel mouse embryonic stem (ES)...

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PMID: 18625891
DOI: 10.1161/circulationaha.108.769562

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