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Article

Multiple parasites mediate balancing selection at two MHC class II genes in the fossorial water vole: insights from multivariate analyses and population genetics.

Journal of evolutionary biology - 1 Sept 2008

Tollenaere C, Bryja J, Galan M, Cadet P, Deter J, Chaval Y, Berthier K, Ribas Salvador A, Voutilainen L, Laakkonen J, Henttonen H, Cosson J-F, Charbonnel N

Abstract excerpt

We investigated the factors mediating selection acting on two MHC class II genes (DQA and DRB) in water vole (Arvicola scherman) natural populations in the French Jura Mountains. Population genetics showed significant homogeneity in allelic frequencies at the DQA1 locus as opposed to neutral markers (nine microsatellites), indicating balancing selection acting on this gene. Moreover, almost exhaustive screening...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 18624885
DOI: 10.1111/j.1420-9101.2008.01563.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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