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Article

Major histocompatibility complex (MHC) heterozygote superiority to natural multi-parasite infections in the water vole (Arvicola terrestris).

Proceedings. Biological sciences - 22 Mar 2009

Oliver M K, Telfer S, Piertney S B

Abstract excerpt

The fundamental role of the major histocompatibility complex (MHC) in immune recognition has led to a general consensus that the characteristically high levels of functional polymorphism at MHC genes is maintained by balancing selection operating through host-parasite coevolution. However, the actual mechanism by which selection operates is unclear. Two hypotheses have been proposed: overdominance (or...

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Identifiers

PMID: 19129114
DOI: 10.1098/rspb.2008.1525
PMCID: PMC2679068

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

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