Article
Respiratory syncytial virus uses a Vps4-independent budding mechanism controlled by Rab11-FIP2.
Proceedings of the National Academy of Sciences of the United States of America - 22 Jul 2008
Utley Thomas J, Ducharme Nicole A, Varthakavi Vasundhara, Shepherd Bryan E, Santangelo Philip J, Lindquist Michael E, Goldenring James R, Crowe James E
Abstract excerpt
Respiratory syncytial virus (RSV) infects polarized epithelia, which have tightly regulated trafficking because of the separation and maintenance of the apical and basolateral membranes. Previously we established a link between the apical recycling endosome (ARE) and the assembly of RSV. The current studies tested the role of a major ARE-associated protein, Rab11 family interacting protein 2 (FIP2) in the virus...
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