Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Neural Induction with Neurogenin1 Increases the Therapeutic Effects of Mesenchymal Stem Cells in the Ischemic Brain

10 Jul 2008

Abstract excerpt

Mesenchymal stem cells (MSCs) have been shown to ameliorate a variety of neurological dysfunctions. This effect is believed to be mediated by their paracrine functions, since these cells rarely differentiate into neuronal cells. It is of clinical interest whether neural induction of MSCs is beneficial for the replacement therapy of neurological diseases. Here we report that expression of Neurogenin1 (Ngn1), a...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Mesenchymal stem cell research
Share to Nerve injury and regeneration
Share to Neurogenesis and neuroplasticity mechanisms

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 18617687
DOI: 10.1634/stemcells.2008-0108

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Neural Induction with Neurogenin1 Increases the Therapeutic Effects of Mesenchymal Stem Cells in the Ischemic BrainPMID 18617687Read ↗

Review: Neuronal Differentiation Protocols of Mesenchymal Stem CellsSemantic proximity Read ↗

Specific induction of neuronal cells from bone marrow stromal cells and application for autologous transplantation.Semantic proximity Read ↗

Gene expression pattern of functional neuronal cells derived from human bone marrow mesenchymal stromal cellsSemantic proximity Read ↗

Epigenetic conversion of human adult bone mesodermal stromal cells into neuroectodermal cell types for replacement therapy of neurodegenerative disordersSemantic proximity Read ↗

Differentiation of Human Mesenchymal Stem Cells towards Neuronal Lineage: Clinical Trials in Nervous System DisordersSemantic proximity Read ↗

Efficient generation of neural stem cell-like cells from adult human bone marrow stromal cellsSemantic proximity Read ↗

Transplantation of motoneuron-enriched neural cells derived from mouse embryonic stem cells improves motor function of hemiplegic mice.Semantic proximity Read ↗

Neurogenin promotes neurogenesis and inhibits glial differentiation by independent mechanisms.Semantic proximity Read ↗

Concise Review: Adult Mesenchymal Stem Cells, Adult Neural Crest Stem Cells, and Therapy of Neurological Pathologies: A State of PlaySemantic proximity Read ↗

Rac1b regulates NT3-stimulated Mek-Erk signaling, directing marrow-isolated adult multilineage inducible (MIAMI) cells toward an early neuronal phenotype.Semantic proximity Read ↗

Neuronal Transcription Factors Induce Conversion of Human Glioma Cells to Neurons and Inhibit TumorigenesisSemantic proximity Read ↗

Neural Stem Cells, Neural Progenitors, and Neurotrophic FactorsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.