Article
Cytokine gene polymorphisms and fatigue in breast cancer survivors: early findings.
Brain, behavior, and immunity - 1 Nov 2008
Collado-Hidalgo Alicia, Bower Julienne E, Ganz Patricia A, Irwin Michael R, Cole Steve W
Abstract excerpt
Converging evidence from basic and clinical studies suggests a role for proinflammatory cytokines in cancer-related fatigue, although the etiology of elevated inflammatory processes is unclear. We examined single nucleotide polymorphisms (SNPs) in the promoters of cytokine genes as genetic risk factors for cytokine-related fatigue in 33 fatigued and 14 non-fatigued breast cancer survivors, focusing on promoter...
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