Article
Bacterial ApbC can bind and effectively transfer iron-sulfur clusters.
Biochemistry - 5 Aug 2008
Boyd Jeffrey M, Pierik Antonio J, Netz Daili J A, Lill Roland, Downs Diana M
Abstract excerpt
The metabolism of iron-sulfur ([Fe-S]) clusters requires a complex set of machinery that is still being defined. Mutants of Salmonella enterica lacking apbC have nutritional and biochemical properties indicative of defects in [Fe-S] cluster metabolism. ApbC is a 40.8 kDa homodimeric ATPase and as purified contains little iron and no acid-labile sulfide. An [Fe-S] cluster was reconstituted on ApbC, generating a...
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