Prevalence of adenomas and hyperplastic polyps in mismatch repair mutation carriers among CAPP2 participants: report by the colorectal adenoma/carcinoma prevention programme 2.

doi:10.1200/JCO.2007.13.2795

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Article

Prevalence of adenomas and hyperplastic polyps in mismatch repair mutation carriers among CAPP2 participants: report by the colorectal adenoma/carcinoma prevention programme 2.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology - 10 Jul 2008

Liljegren Annelie, Barker Gail, Elliott Faye, Bertario Lucio, Bisgaard Marie Luise, Eccles Diana, Evans Gareth, Macrae Finlay, Maher Eamonn, Lindblom Annika, Rotstein Samuel, Nilsson Bo, Mecklin Jukka-Pekka, Möslein Gabriela, Jass Jeremy, Fodde Riccardo, Mathers John, Burn John, Bishop D Timothy

Abstract excerpt

PURPOSE: To determine the prevalence of adenomatous and hyperplastic polyps in a large cohort of individuals with a germline mutation in a mismatch repair (MMR) gene, the major genetic determinant of hereditary nonpolyposis colorectal cancer (HNPCC). These prevalences have been estimated previously in smaller studies, and the results have been found to be variable. PATIENTS AND METHODS: Colorectal...

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Identifiers

PMID: 18612159
DOI: 10.1200/JCO.2007.13.2795
PMCID: PMC2645083

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

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