Article
Characterization of the human CIDEA promoter in fat cells.
International journal of obesity (2005) - 1 Sept 2008
Pettersson A T, Laurencikiene J, Nordström E A, Stenson B M, van Harmelen V, Murphy C, Dahlman I, Rydén M
Abstract excerpt
BACKGROUND: Cell death-inducing DFFA (DNA fragmentation factor-alpha)-like effector A (CIDEA) is a protein that regulates lipolysis in human adipocytes through cross-talk involving tumor necrosis factor-alpha (TNF-alpha). TNF-alpha downregulates CIDEA mRNA although it is unclear whether this is mediated through transcriptional or post-transcriptional mechanisms. CIDEA has important metabolic effects in human fat...
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