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Article

p100 increases AT1R expression through interaction with AT1R 3'-UTR

27 Jun 2008

Abstract excerpt

p100 protein (SND1, Tudor-SN) is a multifunctional protein that functions as a co-activator for several transcription factors, has a role in mRNA processing and participates in RNAi-induced silencing complex (RISC) with yet unknown function. In this study we identified a novel function for p100 as a regulator of angiotensin II type 1 receptor (AT1R) expression. The binding of p100 to AT1R 3'-untranslated region...

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PMID: 18603592
DOI: 10.1093/nar/gkn411

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