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Article

High-density lipoprotein regulates angiogenesis by long non-coding RNA HDRACA

14 Aug 2023

Abstract excerpt

Normal high-density lipoprotein (nHDL) can induce angiogenesis in healthy individuals. However, HDL from patients with coronary artery disease undergoes various modifications, becomes dysfunctional (dHDL), and loses its ability to promote angiogenesis. Here, we identified a long non-coding RNA, HDRACA, that is involved in the regulation of angiogenesis by HDL. In this study, we showed that nHDL downregulates the...

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PMID: 37574469
DOI: 10.1038/s41392-023-01558-6

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