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Article

The Effects of Lentiviral Gene Therapy With Bone Morphogenetic Protein-2-Producing Bone Marrow Cells on Spinal Fusion in Rats

26 Jun 2008

Abstract excerpt

STUDY DESIGN: Rat spinal fusion model. OBJECTIVE: This study aimed to assess the ability of rat bone marrow cells (RBMCs) transfected with bone morphogenetic protein (BMP)-2-containing lentivirus to induce a posterolateral spinal fusion in a rat model. SUMMARY OF BACKGROUND DATA: Spinal arthrodesis is a commonly performed spinal procedure and autograft remains the standard for achieving spinal fusion. However,...

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PMID: 18600149
DOI: 10.1097/bsd.0b013e31814cf51d

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