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Article

Cardiac ion channel gene mutations in sudden infant death syndrome.

Pediatric research - 1 Nov 2008

Otagiri Tesshu, Kijima Kazuki, Osawa Motoki, Ishii Kuniaki, Makita Naomasa, Matoba Ryoji, Umetsu Kazuo, Hayasaka Kiyoshi

Abstract excerpt

Sudden infant death syndrome (SIDS) is multifactorial and may result from the interaction of a number of environmental, genetic, and developmental factors. We studied three major genes causing long QT syndrome in 42 Japanese SIDS victims and found five mutations, KCNQ1-K598R, KCNH2-T895M, SCN5A-F532C, SCN5A-G1084S, and SCN5A-F1705S, in four cases; one case had both KCNH2-T895M and SCN5A-G1084S. All mutations were...

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Source

Identifiers

PMID: 18596570
DOI: 10.1203/PDR.0b013e3181841eca

Genes

KCNH2
KCNQ1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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