Article
An integrative hypothesis about the origin and development of sporadic and familial breast cancer subtypes.
Carcinogenesis - 1 Aug 2008
Melchor Lorenzo, Benítez Javier
Abstract excerpt
Do breast cancer tumours have a common cell origin? Do different breast cancer molecular phenotypes arise from distinct cell types? The studies we have performed during the last few years in familial breast tumours (BRCA1, BRCA2 and non-BRCA1/2) widen questions about the development of sporadic breast cancer to hereditary breast cancer. Array-comparative genomic hybridisation (CGH) studies show universal genomic...
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