A Mechanism for the Inhibition of Neural Progenitor Cell Proliferation by Cocaine

Abstract excerpt

BACKGROUND: Prenatal exposure of the developing brain to cocaine causes morphological and behavioral abnormalities. Recent studies indicate that cocaine-induced proliferation inhibition and/or apoptosis in neural progenitor cells may play a pivotal role in causing these abnormalities. To understand the molecular mechanism through which cocaine inhibits cell proliferation in neural progenitors, we sought to...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Cancer-related Molecular Pathways
• Share to Neurogenesis and neuroplasticity mechanisms
• Share to Prenatal Substance Exposure Effects