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Article

Cortical serotonin type-2 receptor density in parents of children with autism spectrum disorders.

Journal of autism and developmental disorders - 1 Jan 2009

Goldberg Jeremy, Anderson George M, Zwaigenbaum Lonnie, Hall Geoffrey B C, Nahmias Claude, Thompson Ann, Szatmari Peter

Abstract excerpt

Parents (N = 19) of children with autism spectrum disorders (ASD) and adult controls (N = 17) underwent positron emission tomography (PET) using [(18)F]setoperone to image cortical serotonin type-2 (5-HT2) receptors. The 5-HT2 binding potentials (BPs) were calculated by ratioing [(18)F]setoperone intensity in regions of interest (ROI) to cerebellar intensity. Cortical 5-HT2 BPs were significantly lower in parents...

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Identifiers

PMID: 18592367
DOI: 10.1007/s10803-008-0604-4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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