Article
Null allele sequence structure at the DYS448 locus and implications for profile interpretation.
International journal of legal medicine - 1 Sept 2008
Budowle Bruce, Aranda Xavier G, Lagace Robert E, Hennessy Lori K, Planz John V, Rodriguez Manuel, Eisenberg Arthur J
Abstract excerpt
Null alleles can occur with any PCR-based STR typing system. They generally are due to deletions within the target region or primer binding sites or by primer binding site mutations that destabilize hybridization of at least one of the primers flanking the target region. Although not common, null...
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