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Article

MCP-1/CCR2 system is involved in high glucose-induced fibronectin and type IV collagen expression in cultured mesangial cells.

American journal of physiology. Renal physiology - 1 Sept 2008

Park Jehyun, Ryu Dong-Ryeol, Li Jin Ji, Jung Dong-Sub, Kwak Seung-Jae, Lee Sun Ha, Yoo Tae-Hyun, Han Seung Hyeok, Lee Jung Eun, Kim Dong Ki, Moon Sung Jin, Kim Kunhong, Han Dae Suk, Kang Shin-Wook

Abstract excerpt

Monocyte chemoattractant protein-1 (MCP-1) is a potent chemokine that plays an important role in the recruitment of macrophages. Although previous studies have demonstrated the importance of MCP-1 in the pathogenesis of diabetic nephropathy (DN) in terms of inflammation, the role of MCP-1 and its receptor (C-C chemokine receptor 2; CCR2) in extracellular matrix (ECM) accumulation under diabetic conditions has...

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Share to Chemokine CCL2
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Diabetic Nephropathies

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Share to Receptors, CCR2

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Source

Identifiers

PMID: 18579703
DOI: 10.1152/ajprenal.00547.2007

Genes

CCR2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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