Article
The mu opioid receptor A118G gene polymorphism moderates effects of trait anger-out on acute pain sensitivity.
Pain - 15 Oct 2008
Bruehl Stephen, Chung Ok Y, Burns John W
Abstract excerpt
Both trait anger-in (managing anger through suppression) and anger-out (managing anger through direct expression) are related to pain responsiveness, but only anger-out effects involve opioid mechanisms. Preliminary work suggested that the effects of anger-out on postoperative analgesic requirements were moderated by the A118G single nucleotide polymorphism of the mu opioid receptor gene. This study further...
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