Article
High genetic diversity among Mycobacterium tuberculosis complex strains from Sierra Leone.
BMC microbiology - 25 Jun 2008
Homolka Susanne, Post Erik, Oberhauser Barbara, George Abu Garawani, Westman Lars, Dafae Foday, Rüsch-Gerdes Sabine, Niemann Stefan
Abstract excerpt
BACKGROUND: Among tuberculosis (TB) high incidence regions, Sub-Saharan Africa is particularly affected with approx. 1.6 million new cases every year. Besides this dramatic situation, data on the diversity of Mycobacterium tuberculosis complex (MTBC) strains causing this epidemic in this area are only sparsely available. Here we analyzed the population structure of strains from Sierra Leone with a special focus...
Topics
- Antitubercular Agents
- DNA Fingerprinting
- DNA, Intergenic
- Drug Resistance, Multiple, Bacterial
- Genetic Variation
- Humans
- Minisatellite Repeats
- Mycobacterium
- Retrospective Studies
- Sierra Leone