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Article

MYB function in normal and cancer cells.

Nature reviews. Cancer - 1 Jul 2008

Ramsay Robert G, Gonda Thomas J

Abstract excerpt

The transcription factor MYB has a key role as a regulator of stem and progenitor cells in the bone marrow, colonic crypts and a neurogenic region of the adult brain. It is in these compartments that a deficit in MYB activity leads to severe or lethal phenotypes. As was predicted from its leukaemogenicity in several animal species, MYB has now been identified as an oncogene that is involved in some human...

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Identifiers

PMID: 18574464
DOI: 10.1038/nrc2439

Genes

MYB

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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c-MYB and DMTF1 in CancerSemantic proximity Read ↗

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Defective Myb Function Ablates Cyclin E1 Expression and Perturbs Intestinal Carcinogenesis.Semantic proximity Read ↗

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