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Article

Candidate gene analysis in primary lymphedema.

Lymphatic research and biology - 1 Jan 2008

Ferrell Robert E, Kimak Mark A, Lawrence Elizabeth C, Finegold David N

Abstract excerpt

BACKGROUND: Primary lymphedema, the accumulation of protein-rich fluid in the interstitial space, is the clinical manifestation of mutations involved in lymphatic development and function. Mutations in three genes, VEGFR3, FOXC2, and SOX18, cause primary lymphedema. However, mutations in these three genes only account for a fraction of primary lymphedema. To identify other genes mutated in primary lymphedema, we...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 18564921
DOI: 10.1089/lrb.2007.1022

Genes

FABP4
NRP2
SOX17
SYK
EMILIN1
LCP2
RORC
VCAM1
VEGFB
FOXC2
SOX18

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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