Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetic Screening in a Large Cohort of Italian Patients Affected by Primary Lymphedema Using a Next Generation Sequencing (NGS) Approach.

Lymphology - 1 Jun 2016

Michelini S, Vettori A, Maltese P E, Cardone M, Bruson A, Fiorentino A, Cappellino F, Sainato V, Guerri G, Marceddu G, Tezzele S, Bertelli M

Abstract excerpt

Primary lymphedema is a rare inherited condition characterized by swelling of body tissues caused by accumulation of fluid, especially in the lower limbs. In many patients, primary lymphedema has been associated with variations in a number of genes involved in the development and maintenance of the lymphatic system. In this study, we performed a genetic screening in patients affected by primary lymphedema using a...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to GATA2 Transcription Factor
Share to Hepatocyte Growth Factor

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Kinesins

Share to Lymphedema

Share to Proto-Oncogene Proteins c-met

Share to SOXF Transcription Factors

Share to Vascular Endothelial Growth Factor C

Share to Vascular Endothelial Growth Factor Receptor-3

Source

Identifiers

PMID: 29906362

Genes

CCBE1
FLT4
FOXC2
GATA2
GJC2
HGF
MET
SOX18
VEGFC
KIF11

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic Screening in a Large Cohort of Italian Patients Affected by Primary Lymphedema Using a Next Generation Sequencing (NGS) Approach.PMID 29906362Read ↗

Clinical and genetic study of 46 Italian patients with primary lymphedema.Semantic proximity Read ↗

Clinical Staging and Genetic Profiling of Korean Patients with Primary Lymphedema Using Whole-Exome Sequencing: Preliminary ResultsSemantic proximity Read ↗

Mutations in the VEGFR3 Signaling Pathway Explain 36% of Familial LymphedemaSemantic proximity Read ↗

A Multi-Gene Panel to Identify Lipedema-Predisposing Genetic Variants by a Next-Generation Sequencing StrategySemantic proximity Read ↗

Clinical staging and genetic profiling of Korean patients with primary lymphedema using targeted gene sequencingSemantic proximity Read ↗

Candidate gene analysis in primary lymphedema.Semantic proximity Read ↗

Genetic tests in lymphatic vascular malformations and lymphedema.Semantic proximity Read ↗

A Novel Missense Mutation in FLT4 Causes Autosomal Recessive Hereditary Lymphedema.Semantic proximity Read ↗

Digenic Inheritance of a FOXC2 Mutation and Two PIEZO1 Mutations Underlies Congenital Lymphedema in a Multigeneration Family.Semantic proximity Read ↗

Genetic Study of HGF-MET Signaling Pathway in Primary Lymphedema Patients: Supporting Evidence for Loss of Function Variants in HGF.Semantic proximity Read ↗

Increasing evidence of hereditary lymphedema caused by CELSR1 loss‐of‐function variantsSemantic proximity Read ↗

Two rare PROX1 variants in patients with lymphedema.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.