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Article

Possible genetic predisposition to lymphedema after breast cancer.

Lymphatic research and biology - 1 Mar 2012

Newman Beth, Lose Felicity, Kedda Mary-Anne, Francois Mathias, Ferguson Kaltin, Janda Monika, Yates Patsy, Spurdle Amanda B, Hayes Sandra C

Abstract excerpt

BACKGROUND: Known risk factors for secondary lymphedema only partially explain who develops lymphedema following cancer, suggesting that inherited genetic susceptibility may influence risk. Moreover, identification of molecular signatures could facilitate lymphedema risk prediction prior to surgery or lead to effective drug therapies for prevention or treatment. Recent advances in the molecular biology underlying...

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Source

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Identifiers

PMID: 22404826
DOI: 10.1089/lrb.2011.0024
PMCID: PMC3311400

Genes

RORC
ADM
FOXC2
LYVE1
PROX1
SOX18
VEGFC
VEGFD

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