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Universal Primer Set for Amplification and Sequencing of HA 0 Cleavage Sites of All Influenza A Viruses

19 Jun 2008

Abstract excerpt

Sequence analysis of the endoproteolytic cleavage site within the hemagglutinin (HA) precursor protein HA(0) is fundamental for studies of the molecular biology of influenza A viruses, in particular, for molecular pathotyping of subtype H5 and H7 isolates. A current problem for routine diagnostics is the emergence of new strains of the H5 or H7 subtype or even other subtypes which escape detection by commonly...

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PMID: 18562585
DOI: 10.1128/jcm.00466-08

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