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Article

W43X SDHD mutation in sporadic head and neck paraganglioma.

Analytical and quantitative cytology and histology - 1 Apr 2008

Galera-Ruiz Hugo, Gonzalez-Campora Ricardo, Rey-Barrera Manuel, Rollón-Mayordomo Angel, Garcia-Escudero Antonio, Fernández-Santos José M, DeMiguel Manuel, Galera-Davidson Hugo

Abstract excerpt

OBJECTIVE: To analyze the presence of SDHD gene mutations in patients with sporadic head and neck paraganglioma. STUDY DESIGN: The presence of somatic and germline SDHD mutations was investigated in 10 patients by polymerase chain reaction and direct sequencing. RESULTS: Two patients displayed mutations: 259C>T (P87S) in 1 case and 129G>A (W43X) in the other. The first was considered a neutral polymorphism. The...

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Source

Identifiers

PMID: 18561749

Genes

SDHD

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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