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Article

High prevalence of SDHB mutations in head and neck paraganglioma in Belgium.

Journal of hypertension - 1 Jul 2008

Persu Alexandre, Hamoir Marc, Grégoire Vincent, Garin Pierre, Duvivier Etienne, Reychler Hervé, Chantrain Gilbert, Mortier Geert, Mourad Michel, Maiter Dominique, Vikkula Miikka

Abstract excerpt

BACKGROUND: Recent reports have found genetic mutations in up to one quarter of patients harbouring pheochromocytoma and/or paraganglioma. This high prevalence was mainly due to the discovery of the role of SDH genes. While SDHD has been more frequently associated with the pathogenesis of head and neck paragangliomas, SDHB mutations were mainly associated with malignant and/or extra-adrenal...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 18551016
DOI: 10.1097/HJH.0b013e3282ffdc54

Genes

SDHB
SDHD
RET
VHL

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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