Article
Peroxisome proliferator-activated receptor gamma-2 P12A polymorphism and risk of acute myocardial infarction, coronary heart disease and ischemic stroke: a case-cohort study and meta-analyses.
Vascular health and risk management - 1 Jan 2008
Zafarmand Mohammad Hadi, van der Schouw Yvonne T, Grobbee Diederick E, de Leeuw Peter W, Bots Michiel L
Abstract excerpt
BACKGROUND: The alanine allele of P12A polymorphism in PPARG gene in a few studies has been associated with a reduced or increased risk of acute myocardial infarction (AMI). Yet, the risk relation has not been confirmed, and data on ischemic stroke (IS) is scarce. We therefore investigated the role of this polymorphism on occurrence of AMI, coronary heart disease (CHD) and IS. METHODS AND FINDINGS: We performed a...
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