Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The round window membrane in otitis media: effect of pneumococcal proteins.

Archives of otolaryngology--head & neck surgery - 1 Jun 2008

Schachern Patricia, Tsuprun Vladimir, Cureoglu Sebahattin, Ferrieri Patricia, Briles David, Paparella Michael, Juhn Steven

Abstract excerpt

OBJECTIVE: To determine whether mutants of Streptococcus pneumoniae that are deficient in pneumococcal surface protein A (PspA), pneumococcal surface antigen A (PsaA), or pneumolysin (Ply) are less virulent and less likely to penetrate the round window membrane (RWM). DESIGN: Histopathologic comparison of wild-type S. pneumoniae and its mutants deficient in PspA, PsaA, and Ply. SETTING: Otopathology Laboratory,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bacterial Proteins
Share to Mutation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Otitis Media

Share to Streptococcus pneumoniae

Share to Streptolysins

Source

Identifiers

PMID: 18559736
DOI: 10.1001/archotol.134.6.658

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 10 closest

The round window membrane in otitis media: effect of pneumococcal proteins.PMID 18559736Read ↗

Development of a non-invasive murine infection model for acute otitis media.Semantic proximity Read ↗

Interaction of phase variation, host and pressure/gas composition: pneumococcal gene expression of PsaA, SpxB, Ply and LytA in simulated middle ear environments.Semantic proximity Read ↗

Prospects for prevention of otitis media.Semantic proximity Read ↗

Strain-specific virulence phenotypes of Streptococcus pneumoniae assessed using the Chinchilla laniger model of otitis media.Semantic proximity Read ↗

Streptococcus pneumoniae-induced ototoxicity in organ of Corti explant cultures.Semantic proximity Read ↗

Role of the alternative and classical complement activation pathway in complement mediated killing against Streptococcus pneumoniae colony opacity variants during acute pneumococcal otitis media in mice.Semantic proximity Read ↗

[Molecular analysis of pathogens of upper respiratory tract infections in children--a study of nasopharyngeal S. pneumoniae and PBP genes in acute otitis media].Semantic proximity Read ↗

Contribution of mucoviscosity-associated gene A (magA) to virulence in experimental Klebsiella pneumoniae endophthalmitis.Semantic proximity Read ↗

Persistent measles virus infection as a possible cause of otosclerosis: state of the art.Semantic proximity Read ↗

Effect of influenza A virus infection on nasopharyngeal colonization and otitis media induced by transparent or opaque phenotype variants of Streptococcus pneumoniae in the chinchilla model.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.