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Article

Trafficking of cholinesterases and neuroligins mutant proteins. An association with autism.

Chemico-biological interactions - 25 Sept 2008

De Jaco Antonella, Comoletti Davide, King Charles C, Taylor Palmer

Abstract excerpt

Autism encompasses a wide spectrum of disorders arising during brain development. Recent studies reported that sequence polymorphisms in neuroligin-3 (NLGN3) and neuroligin-4 (NLGN4) genes have been linked to autism spectrum disorders indicating neuroligin genes as candidate targets in brain disorders. We have characterized a single mutation found in two affected brothers that substituted Arg451 to Cys in NL3....

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Source

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Identifiers

PMID: 18555979
DOI: 10.1016/j.cbi.2008.04.023
PMCID: PMC2692863

Genes

NLGN3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Trafficking of cholinesterases and neuroligins mutant proteins. An association with autism.PMID 18555979Read ↗

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Autism-associated variants of neuroligin 4X impair synaptogenic activity by various molecular mechanismsSemantic proximity Read ↗

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