Article
Genetic heterogeneity in ADHD: DAT1 gene only affects probands without CD.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 5 Dec 2008
Zhou Kaixin, Chen Wai, Buitelaar Jan, Banaschewski Tobias, Oades Robert D, Franke Barbara, Sonuga-Barke Edmund, Ebstein Richard, Eisenberg Jacques, Gill Michael, Manor Iris, Miranda Ana, Mulas Fernando, Roeyers Herbert, Rothenberger Aribert, Sergeant Joseph, Steinhausen Hans-Christoph, Lasky-Su Jessica, Taylor Eric, Brookes Keeley J, Xu Xiaohui, Neale Benjamin M, Rijsdijk Fruhling, Thompson Margaret, Asherson Philip, Faraone Stephen V
Abstract excerpt
Previous studies have found heterogeneous association between DAT1-3'-UTR-VNTR and attention deficit hyperactivity disorder (ADHD). Various proportions of conduct disorder (CD) comorbidity in their ADHD samples may partially explain the observational discrepancies. Evidence for this comes from family and twin studies which found ADHD probands with CD (ADHD + CD) are genetically different from those without CD...
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