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Article

Recent adaptive selection at MAOB and ancestral susceptibility to schizophrenia.

American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 5 Apr 2009

Carrera Noa, Sanjuán Julio, Moltó María Dolores, Carracedo Angel, Costas Javier

Abstract excerpt

The ancestral susceptibility hypothesis has been proposed to explain the existence of susceptibility alleles to common diseases. Some ancestral alleles, reflecting ancient adaptations, may be poorly adapted to the more contemporary environmental conditions giving rise to an increased risk to suffer some common disorders. In order to test this hypothesis in schizophrenia, we focused on the monoamine oxidase B gene...

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Source

Identifiers

PMID: 18553363
DOI: 10.1002/ajmg.b.30823

Genes

MAOB

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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