Article
Machine-learning approaches for classifying haplogroup from Y chromosome STR data.
PLoS computational biology - 13 Jun 2008
Schlecht Joseph, Kaplan Matthew E, Barnard Kobus, Karafet Tatiana, Hammer Michael F, Merchant Nirav C
Abstract excerpt
Genetic variation on the non-recombining portion of the Y chromosome contains information about the ancestry of male lineages. Because of their low rate of mutation, single nucleotide polymorphisms (SNPs) are the markers of choice for unambiguously classifying Y chromosomes into related sets of l...
Topics
- Algorithms
- Artificial Intelligence
- Chromosome Mapping
- Chromosomes, Human, Y
- DNA Mutational Analysis
- Evolution, Molecular
- Genetic Variation
- Haplotypes
- Humans
- Microsatellite Repeats
- Mutation
- Pattern Recognition, Automated