Article
Improving the regional Y-STR haplotype resolution utilizing haplogroup-determining Y-SNPs and the application of machine learning in Y-SNP haplogroup prediction in a forensic Y-STR database: A pilot study on male Chinese Yunnan Zhaoyang Han population.
Forensic science international. Genetics - 1 Mar 2022
Yin Caiyong, He Ziwei, Wang Yi, He Xi, Zhang Xiao, Xia Mingying, Zhai Dian, Chang Kaichuang, Chen Xueyun, Chen Xingneng, Chen Feng, Jin Li, Li Shilin
Abstract excerpt
Improving the resolution of the current widely used Y-chromosomal short tandem repeat (Y-STR) dataset is of great importance for forensic investigators, and the current approach is limited, except for the addition of more Y-STR loci. In this research, a regional Y-DNA database was investigated to improve the Y-STR haplotype resolution utilizing a Y-SNP Pedigree Tagging System that includes 24 Y-chromosomal single...
Topics
- China
- Chromosomes, Human, Y
- Genetics, Population
- Haplotypes
- Humans
- Machine Learning
- Male
- Microsatellite Repeats
- Pilot Projects
- Polymorphism, Single Nucleotide