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Article

Discriminating between varicella-zoster virus vaccine and wild-type strains by loop-mediated isothermal amplification.

Journal of clinical microbiology - 1 Aug 2008

Higashimoto Yuki, Ihira Masaru, Ohta Akane, Inoue Shigeki, Usui Chie, Asano Yoshizo, Yoshikawa Tetsushi

Abstract excerpt

The loop-mediated isothermal amplification (LAMP) method was developed to distinguish between the varicella-zoster virus (VZV) vaccine (vOka) strain and wild-type strains. Two single nucleotide polymorphisms (SNPs) (nucleotide [nt] 105705 for VR-1 VZV LAMP and nt 106262 for VR-2 VZV LAMP) located in the open reading frame 62 gene were selected as LAMP targets. Amplified vOka DNA demonstrated a typical ladder...

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Identifiers

PMID: 18550736
DOI: 10.1128/JCM.00216-08
PMCID: PMC2519472

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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