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Article

Rapid genotyping of varicella-zoster virus vaccine and wild-type strains with fluorophore-labeled hybridization probes.

Journal of clinical microbiology - 1 Dec 2000

Loparev V N, McCaustland K, Holloway B P, Krause P R, Takayama M, Schmid D S

Abstract excerpt

We developed a single-tube rapid method for the detection and differentiation of varicella-zoster virus (VZV) vaccine and wild-type strains that combines rapid-cycle PCR with wild-type-specific fluorescent probe melting profiles for product genotyping. A region including the polymorphic site in VZV open reading frame (ORF) 62 was amplified in the presence of two fluorescence-labeled hybridization probes. During...

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Identifiers

PMID: 11101557
DOI: 10.1128/JCM.38.12.4315-4319.2000
PMCID: PMC87598

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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