Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Repeated temperature fluctuation extends the life span of Caenorhabditis elegans in a daf-16-dependent fashion.

Mechanisms of ageing and development - 1 Sept 2008

Galbadage Thushara, Hartman Phil S

Abstract excerpt

Thermocyclers were utilized to regularly shift nematodes between 12 degrees C and 25 degrees C throughout their life spans. When wild-type worms (N2) were "thermocycled" between 12 degrees C and 25 degrees C at 10-min intervals they lived almost as long as those that were incubated constantly at 12 degrees C. Shifting at 1-min or 1-h intervals lessened this effect. Similar results were observed for the long-lived...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Animals, Genetically Modified
Share to Caenorhabditis elegans

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Caenorhabditis elegans Proteins

Share to Forkhead Transcription Factors

Share to Genes, Helminth

Share to Hot Temperature

Share to Longevity

Share to Oxidative Stress

Source

Identifiers

PMID: 18538371
DOI: 10.1016/j.mad.2008.04.012

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Repeated temperature fluctuation extends the life span of Caenorhabditis elegans in a daf-16-dependent fashion.PMID 18538371Read ↗

One-day thermal regime extends the lifespan in Caenorhabditis elegansSemantic proximity Read ↗

Longevity and heat stress regulation in Caenorhabditis elegans.Semantic proximity Read ↗

External induction of heat shock stimulates the immune response and longevity of Caenorhabditis elegans towards pathogen exposure.Semantic proximity Read ↗

Heat shock protein accumulation is upregulated in a long-lived mutant of Caenorhabditis elegans.Semantic proximity Read ↗

Thermotolerance and extended life-span conferred by single-gene mutations and induced by thermal stress.Semantic proximity Read ↗

Thermotolerance of a long-lived mutant of Caenorhabditis elegans.Semantic proximity Read ↗

Molecular genetic mechanisms of life span manipulation in Caenorhabditis elegans.Semantic proximity Read ↗

Regulation of aging by unc-13 and sbt-1 in Caenorhabditis elegans is temperature-dependent.Semantic proximity Read ↗

Lifespan extension in <i>C. elegans</i> by a molecular chaperone dependent upon insulin‐like signalsSemantic proximity Read ↗

HIF-1 is required for heat acclimation in the nematode Caenorhabditis elegans.Semantic proximity Read ↗

Caenorhabditis elegans Genes Affecting Interindividual Variation in Life-span Biomarker Gene Expression.Semantic proximity Read ↗

Pathogen-induced Caenorhabditis elegans developmental plasticity has a hormetic effect on the resistance to biotic and abiotic stresses.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.