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Article

Phenotypic variants of the deafness-associated mitochondrial DNA A7445G mutation.

Current medicinal chemistry - 1 Jan 2008

Maász Anita, Komlósi Katalin, Hadzsiev Kinga, Szabó Zsolt, Willems Patrick J, Gerlinger Imre, Kosztolányi György, Méhes Károly, Melegh Béla

Abstract excerpt

A number of nuclear and mitochondrial mutations have been implicated in non-syndromic hearing loss. Among them, various mutations of mitochondrial Ser(UCN)-tRNA and 12S rRNA genes have been found to be associated with deafness; the A7445G mitochondrial DNA (mtDNA) in this group is unique, simultaneously affecting two different mitochondrial genes, encoding the Ser(UCN)-tRNA and the first subunit of cytochrome...

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PMID: 18537605
DOI: 10.2174/092986708784534910

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UCN

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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