Article
Functional characterization of the histidine kinase of the E. coli two-component signal transduction system AtoS-AtoC.
Biochimica et biophysica acta - 1 Sept 2008
Filippou Panagiota S, Kasemian Lucy D, Panagiotidis Christos A, Kyriakidis Dimitrios A
Abstract excerpt
The Escherichia coli AtoS-AtoC two-component signal transduction system regulates the expression of the atoDAEB operon genes, whose products are required for short-chain fatty acid catabolism. In this study purified his-tagged wild-type and mutant AtoS proteins were used to prove that these proteins are true sensor kinases. The phosphorylated residue was identified as the histidine-398, which was located in a...
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