Article
Molecular genetics of hereditary renal cancer: new genes and diagnostic and therapeutic opportunities.
Expert review of anticancer therapy - 1 Jun 2008
Hansel Donna E, Rini Brian I
Abstract excerpt
Renal cell carcinoma may be sporadic or occur in the setting of an inherited cancer syndrome, such as von Hippel-Lindau or Birt-Hogg-Dube syndrome. Although the clinical spectrum of heritable renal cancer syndromes varies significantly, commonalities include the often young age of presentation, multifocal and bilateral nature of renal lesions, and autosomal dominant pattern of inheritance. Molecular studies have...
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