Article
Advances in Molecular Mechanisms of Kidney Disease: Integrating Renal Tumorigenesis of Hereditary Cancer Syndrome.
International journal of molecular sciences - 21 Aug 2024
Cicchetti Rossella, Basconi Martina, Litterio Giulio, Mascitti Marco, Tamborino Flavia, Orsini Angelo, Digiacomo Alessio, Ferro Matteo, Schips Luigi, Marchioni Michele
Abstract excerpt
Renal cell carcinoma (RCC) comprises various histologically distinct subtypes, each characterized by specific genetic alterations, necessitating individualized management and treatment strategies for each subtype. An exhaustive search of the PubMed database was conducted without any filters or restrictions. Inclusion criteria encompassed original English articles focusing on molecular mechanisms of kidney cancer....
Topics
- Humans
- Kidney Neoplasms
- Neoplastic Syndromes, Hereditary
- Genetic Predisposition to Disease
- Carcinoma, Renal Cell
- Mutation
- Carcinogenesis
- Tumor Suppressor Proteins